Can live attenuated virus work as post-exposure treatment?
نویسندگان
چکیده
Simple mathematical models for the competition between different virus variants in the presence of a crossreactive immune response show that, contrary to expectation, selection can favour variants that induce low viral loads. Here, Sebastian Bonhoeffer and Martin Nowak suggest that such 'competitively superior', but 'less pathogenic', mutants may be a possibility for post-exposure treatment of persistent virus infections.
منابع مشابه
Mass immunization of children in Iran with live attenuated Sugiyama measles virus adapted to calf kidney cell cultures
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Efficacy and safety of live attenuated Sugiyama strain of measles virus in mass immunization of children in rural regions of Iran
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Rabies Control and Treatment: From Prophylaxis to Strategies with Curative Potential
Rabies is an acute, fatal, neurological disease that affects almost all kinds of mammals. Vaccination (using an inactivated rabies vaccine), combined with administration of rabies immune globulin, is the only approved, effective method for post-exposure prophylaxis against rabies in humans. In the search for novel rabies control and treatment strategies, live-attenuated viruses have recently em...
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عنوان ژورنال:
- Immunology today
دوره 16 3 شماره
صفحات -
تاریخ انتشار 1995